Tabtoxinine β-lactam

Tabtoxinine β-lactam
Identifiers
CAS number 65709-93-5 Y
PubChem 3035052
ChemSpider 24751854
Jmol-3D images Image 1
Properties
Molecular formula C7H12N2O4
Molar mass 188.18 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Tabtoxinine β-lactam is a monobactam antibiotic derived from tabtoxin. Unlike other β-lactam antibiotics, which inhibit penicillin-binding proteins, tabtoxinine β-lactam inhibits glutamine synthetase.[1]

References

  1. ^ Thomas, M. D.; Langston-Unkefer, P. J.; Uchytil, T. F.; Durbin, R. D. (1983). "Inhibition of Glutamine Synthetase from Pea by Tabtoxinine-β-lactam". Plant physiology 71 (4): 912–915. PMC 1066143. PMID 16662928. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1066143.  edit